Job description
The postholder will lead delivery of a KTP project to develop a model which supports microbial growth without oxygen, whilst also providing conditions with oxygen to support growth of epithelial cells. This dual feature will enable better simulation of the colonic environment than existing in vitro gut models. The model will be inexpensive, flexible and reduce the need for animal testing.
Your role will develop and refine the model for testing anaerobic bacteria:host cell interactions and validate the model through specific test experiments.
Project description
To refine, validate and commercialise a pre-clinical model of the human gut barrier. The model will be used to study microbes with important roles in health and disease, generate better insights on microbial interactions within the gut and support new therapeutic development for inflammatory bowel disease, liver disease and cancer.
About the business
NCIMB is an established biotechnology company providing innovative microbial services for sectors including life sciences, food and drink, energy, and environmental services.
Life Sciences
Microbiology
PhD Microbiology or equivalent
26 April 2024
19 May 2024
ROW123R
The postholder will lead delivery of a KTP project to develop a model which supports microbial growth without oxygen, whilst also providing conditions with oxygen to support growth of epithelial cells. This dual feature will enable better simulation of the colonic environment than existing in vitro gut models. The model will be inexpensive, flexible and reduce the need for animal testing.
Your role will develop and refine the model for testing anaerobic bacteria:host cell interactions and validate the model through specific test experiments.